Wednesday, May 5, 2010

Buffalo Select Chorus on Buffalo Place for May 26 with Joseph Wooten

Buffalo Select Chorus, with national recording artist Joseph Wooten, will perform their 5th Annual Concert on Wednesday, May 26th at 7:30 p.m. at Asbury Hall at Babeville.  The concert and reception to follow is free and open-to-the-public.  The evening is a mixed musical repertoire of local musicians and the supremely talented Buffalo Select Chorus under the direction and guidance of Musical Director, Linda Lombardo Appleby.

Buffalo Select Chorus is the only chorus made up of Buffalo high school students, with nine different schools represented.  The Chorus is a talented, dynamic group that has persevered despite challenges for funding in the arts in the Buffalo schools.  The Chorus has grown exponentially over several years and in partnership with the Righteous Babe Foundation, will continue its mission to provide a venue for Buffalo High School students to expand their vocal skills while offering actual performance experience under the tutelage of certified music teachers and professional musicians.  This program of excellence will also be saying goodbye to many graduating seniors.

Buffalo Select Chorus can be heard rehearsing every Monday night at Asbury Hall and their annual concert is not one to miss.  To donate, purchase a CD or for more information search HERE on facebook for Buffalo Select Chorus.  Abury Hall at Babeville is located at 341 Delaware Avenue.

Read on Buffalo Place HERE 

Buffalo Select Chorus/Joseph Wooten: Live at Asbury Hall: May 26



Buffalo Select Chorus, with national recording artist Joseph Wooten, perform their 5th Annual Concert May 26 at 7PM LIVE at Asbury Hall at Babeville. The concert and reception to follow is free and open to all public.  The evening is a mixed musical repertoire of local musicians and the supremely talented Buffalo Select Chorus under the direction and guidance of Musical Director, Linda Lombardo Appleby. 

Buffalo Select Chorus is the only chorus made up of Buffalo high school students, with nine different schools represented. The  Chorus is a talented, dynamic group that has persevered despite challenges for funding in the arts in the Buffalo schools.

In spring 2005, Linda Appleby (creative director and vocal instructor), and interested community members and parents set out to create a citywide Buffalo Public High School Chorus.  The group would have weekly practices, play in a variety of venues over the year, have a final concert and reception, and produce a professional recording for use in the college application process.  What resulted from their efforts was a selection of talented individuals from Buffalo Public High Schools who gathered to rehearse once a week for six months.

The Chorus has grown exponentially over several years, and in partnership with the Righteous Babe Foundation, will continue its mission: to provide a venue for Buffalo High School students to expand their vocal skills while offering actual performance experience under the tutelage of certified music teachers and professional musicians. This program of excellence will also be saying goodbye to many graduating seniors.
 
Buffalo Select Chorus can be heard rehearsing every Monday night at Asbury Hall and their annual concert is not one to miss. To donate, purchase a CD or for more information, visit: FACEBOOK.  May 26th, 7:30 pm, Asbury Hall at Babeville on Delaware Avenue, Buffalo,  NY.  The concert and reception is FREE and open to ALL public.

The students that put the "Select" in Buffalo Select Chorus are a much desired investment.

Wednesday, April 28, 2010

Artists United For Human Rights: Anuradha Koirala on CNN

"Please Tell The World About My Girls" 
Anuradha Koirala, Founder of Maiti Nepal 

"On behalf of these unspeakably abused children, we thank you from the bottom of our hearts.  They are defenseless and abandoned persons who now suffer with no hope and in their short lives “ never had a chance”

Barring breaking news, the CNN HEROES profile of Anuradha Koirala is scheduled to premiere THURSDAY, APRIL 29, 2010 at some point during the hour of Larry King Live (9-10pm EST) and re-air during the slotted times, EST, listed below.  

Beginning Friday (4/30/2010--EST), the story will also be available and viewable online at CNN HEROES 

Thanks to everyone for your assistance with this story!  

Best,  Ebonne

AIR SCHEDULE, CNN HEROES: ANURADHA KOIRALA

FRIDAY (4/30) EST
CNN: 8-9a, 11a-12p, 2-3p
*may get extra airing in 3p hr
HLN: 6:30-7a, 1:30-2p, 5-6p, 8-9p/10-11p/1-2a
*may also air in 7:30a hr
CNNI: 2a, 7a, 12p, 8p
  
SATURDAY (5/1) EST
CNN: 10-11a, 3-4p, 5-6p, 11p-12a/2-3a
HLN: 8-8:30a, 2-2:30p
  
CNN en Espanol
Monday (5/3): Premiere in Panorama Mundial 9pm EST

Tuesday (5/4/2010):
- Al Dia 7am EST
- Nuestro Mundo 2pm EST
- Encuentro 6pm EST
- Directo 7pm EST

Sunday (5/2/2010): Mirador Mundial 7pm EST

Friends of Maiti Nepal 
501 (c) 3 Massachusetts non profit corporation
Brigitte Cazalis-Collins (Exec Director)
Joseph H. Collins (Assoc. Director)
63-6 Commercial Wharf Boston MA 02110 USA 

Thursday, April 15, 2010

Rosie's Therapy Muscular Dystrophy UB School of Medicine


Duchenne Muscular Dystrophy is the most common genetic disease of boys.  There is no known therapy or cure.  In 1984 Sachs Lab, University at Buffalo's School of Medicine, Dr. Frederick Sachs, UB Distinguished Professor of Biophysics, Department of Physiology and Biophysics, and his colleagues, have discovered mechanosensitive ion channels, pores in the cell membrane that open under mechanical stress.  When the genetic defects of dystrophy break down reinforcement of the cell membrane, these channels become activated and let calcium leak into the cell causing the muscles to atrophy.  This is what causes muscular dystrophy.

Sachs Lab made the discovery of the channels when there were no drugs known to affect those channels.  Taking a wild chance on Nature's chemical libraries, they examined venoms from scorpions, centipedes and spiders and in a tarantula venom, they discovered a drug that did work. The drug turned out to be a small, non-toxic, protein.  Keep in mind, everything in a venom is not poisonous.  The lab tested the protein (known as GsMTx4) on isolated dystrophic muscle since dystrophin makes a reinforcing network under the cell membrane, and its loss transfers stress to the membrane. This increased stress turns on the channels producing the calcium leak.

GsMTx4 caused the muscle less likely to be damaged from stress. In collaboration with Dr. Eric Hoffman of the Wellstone Institute for Muscular Dystrophy in Washington, Sachs Lab tested GsMTx4, and after a month of treatment there were no significant side effects.

Sachs Lab is close to having a therapy for muscular dystrophy.

To handle commercialization of GsMtx4 after preclinical testing, Sachs Lab formed Rose Pharmaceuticals, a research-based biotech drug company founded with the specific goal of treating muscular dystrophy.  Rose Pharmaceuticals is located in Buffalo and started by Drs. Fred Sachs, Phil Gottlieb and Tom Suchyna and Mr. Jeff Harvey, and Rosie, the tarantula.
Sachs Lab has found a therapy for muscular dystrophy.  There is no known therapy or medication for this condition.  Sachs Lab and Rose Pharmaceuticals is in need of funding and support in order for this therapy to pass FDA Regulation for pre -clinical testing.  The least amount needed is 1.5 million dollars.  Dr. Frederich Sachs speaks of Rosie's Therapy on my radio show, This is NOT The Apple and information can be found at Sachs Lab at UB School of Medicine and Facebook HERE under: Rosie's Therapy for Muscular Dystrophy.  

You can help the research.  Donate (tax deductible) to the lab by sending whatever amount you feel is appropriate for "unrestricted research funds" to:    Rosie's Therapy for Muscular Dystophy:    Grammostola Spatulata Fund UB Foundation P.O. Box 900 Buffalo, NY 14226.

When this therapy passes FDA regulations and pre-clinical testing, not only will there be a therapy for muscular dystrophy, but this medication GsMTx4, with no known side effects, will also be able to treat other conditions that affect muscle walls such as various heart conditions and everyday chronic and acute pain.   Right now, the only medications available for such conditions, including muscular dystrophy have severe side effects and are addictive.

Please join Sachs Lab, Rose Pharmaceuticals and the UB School of Medicine (all Buffalo based entities), in passing a medication that can literally help millions of people. Currently, everyone at Sachs Lab is funding this endeavor out of their own pockets.

Rose Pharmaceuticals has been featured in The UB Reporter,  Technology Transfer Tactics, Innovations Report.com, Fox News National, Buffalo State News, Futurity.org Health & Medicine, and Channel 2 WGRZ. on National News.

The drug is in preclinical trials at the Wellstone Institute in Washington DC.  There is no toxicity.  There are no known side effects.  There are no known addictive properties.  There is no cure or therapy. 

Until now.

You can help the research.  Donate.
 


© Susan Marie 2010
Sachs Lab, Dr. Frederick Sachs
University at Buffalo School of Medicine
Rose Pharmaceuticals